‘Grey’s Anatomy’ Actor, Eric Dane Stars On ‘Brilliant Minds 2’, His Character Also Has ALS Like Him?

Brilliant Minds first premiered last year on September 23, 2024. Since then, the show has captured viewers’ hearts with its focus on neurology and mental health. The medical drama got renewed for a second season recently and has been airing on platforms like NBC and Peacock since November 10, 2025. You might not want to miss tonight’s episode of the show titled, The Firefighter, because it has a special appearance by one of our favourite actors, Eric Dane. Here’s what we know about his role in the show.  

Eric Dane’s role as a firefighter battling ALS on Brilliant Minds 

Eric Dane is popularly known by movie fanatics for his role as ‘Dr. Mark Sloan’, affectionately known as ‘McSteamy’, on the hit series, Grey’s Anatomy. Having played this role for 6 seasons straight, Dane is making a notable return to the small screen with the second season of the medical drama, Brilliant Minds. What makes his debut in this drama special is that he will portray a firefighter named ‘Matthew’, who grapples with the same medical condition that the actor himself has — ALS, short for Amyotrophic Lateral Sclerosis. In an April 10, 2025, interview with People, Dane publicly acknowledged and disclosed his diagnosis of this progressive neurological disease and said how fortunate he was to be able to keep working despite his diagnosis.  

Eric Dane on Brilliant Minds

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